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Achromatopsia
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Achromatopsia is a type of cone dystrophy where there are normally problems only with vision from cone photoreceptors, the ones responsible for color and day vision and visual acuity.
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Adult Stem Cell
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see Stem Cell
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Age-Related Eye Disease Study
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see AREDS
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Age-Related Macular Degeneration (AMD)
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Age-related macular degeneration is a retinal degenerative disease that causes a progressive loss of central vision. AMD is the most common cause of blindness and vision impairment in Americans aged 60 and older. There are two types of AMD: dry (earlier stage) and wet (later stage).
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AMD
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see Age-Related Macular Degeneration
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Angiogenesis
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The growth of new blood vessels. When growing in places they shouldn't, they can cause disease, such as wet age-related macular degeneration (AMD).
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Antioxidant
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A nutritional supplement (like vitamins C or E), drug, or naturally occurring product that protects cells from damage induced by light, stress or metabolic processes (called oxidation). Antioxidants are also prevalent in foods, such as vegetables and fruits.
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Apoptosis or Programmed Cell Death
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A controlled process for cell death, triggered by a signal or biochemical reaction, in response to an accumulation of cellular damage.
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AREDS (Age-Related Eye Disease Study)
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A clinical study that determined a specific nutritional supplementation regimen for prolonging retention of vision in individuals with age-related macular degeneration (AMD).
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Autosomal Dominant Disease
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Disease caused when an individual inherits a disease-causing mutation in one copy of a gene pair.
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Autosomal Recessive Disease
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Disease caused when an individual inherits a mutation(s) that may not cause disease unless both copies of a gene pair are mutated.
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Autosome
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Any chromosome within the 22 pairs of non-sex (not X or Y) chromosomes inherited by every individual from their biological parents.
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Bardet-Biedl Syndrome (BBS)
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Bardet-Biedl syndrome is a complex disorder that affects many parts of the body including the retina. Individuals with BBS have a retinal degeneration similar to retinitis pigmentosa (RP).
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BBS
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see Bardet-Biedl Syndrome
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Best Disease
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Best disease is an inherited form of juvenile macular degeneration characterized by a loss of central vision.
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Beta-carotene
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A nutritional pigment (and antioxidant) that can be used in the visual cycle of the eye. It is responsible for the orange color of carrots and other fruits and vegetables.
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Bruch's membrane
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The blood-retina barrier that separates the retina from the rest of the body, that is often broken in individuals with wet AMD.
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Carotenoids
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Tetraterpenoid organic pigments that are naturally occurring in the chloroplasts and chromoplasts of plants and some other photosynthetic organisms like algae, some bacteria, and some types of fungus.
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CBT
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see Cell-Based Therapy
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Cell
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The smallest building-block of a living being that is capable of functioning on its own.
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