Background
Gray font color on white background Black font color on white background White font color on black background White font color on dark blue background
Font Size
She really loves to suck cock and I love to film her sucking my penis This horny wife gives a blowjob licking the shaft of her husbands hard cock and then taking into her mouth Vegetables are healthy you know? My pussy is realy hungry and wants something inside I dildo the fuck out of my wet pussy thinking of how much cum my boss has filled me with Steaming hot hardcore porn videos turned on brunette babe with massive boobs in fishnet stocking home porn videos and high heels fingers her tight wet honey pot She earned every drop of my cum she give the best sloppy ameteur anal head ever sucking black cock This chick felt both our crotches back in the club office porn she knew she was in for a fun night She said she craved black cock and wanted to walk funny next day This horny husband finds his wife ironing in the porn tube kitchen and puts her down on the floor and fucks her doggystyle Young in love couple making homemade ebony sex porn letting him lick her out and insert himself deep and hard Flashing my sexy thong up my skirt porn stars then get cock stuffed up my cunt mature amateur sex movie This cock hungry brunette milf sucks on hard cock and then gets her mobile porn face covered with cum and her mouth filled up too as a bonus Seksi dekolte kiyafetli Macar kizlar yakin arkadasi ile evde porno hikaye sIkisme doyumsuz sex arzulari sinirsiz yasayip porno duskunu adami doyurma Japon ciplak porno hatun dar gotten yemis cilginca inliyor yarrak kicina girdigi goguslu sicak doyumsuz kiz ask yasamak erotik hikayeler sirada en cok zevk aldigi video ile gosterimi pornoda izle.
Eye Conditions » Usher Syndrome
PDF Print E-mail Bookmark Share This Page

What is Usher Syndrome?

What is Usher Syndrome?

Usher syndrome is an inherited condition characterized by hearing impairment and progressive vision loss. The vision loss is due to retinitis pigmentosa (RP), a degenerative condition of the retina, and usually appears during adolescence or early adulthood. Balance may also be affected. Symptoms vary from person to person and progress at different rates.

Researchers funded by The Foundation Fighting Blindness (FFB) are studying causes and potential treatments for Usher syndrome and other retinal degenerative diseases. Excellent progress in research has been made recently.

There are at least three different forms of Usher syndrome. People with Usher syndrome type 1 (USH1) are usually born with severe hearing loss and experience problems with balance. The first signs of RP — night blindness and loss of peripheral vision — usually appear in early adolescence.

In Usher syndrome type 2 (USH2), newborns have moderate to severe hearing impairment. Symptoms of RP typically start shortly after adolescence. Visual problems progress less rapidly than in Usher type 1 and hearing loss usually remains stable.

A rarer third type of Usher syndrome (USH3) was documented in 1995. Children with USH3 are usually born with good or only mild impairment of hearing. Their hearing and vision loss is progressive, starting around puberty. Balance may also be affected.

Hearing loss in Usher syndrome is due to a genetic mutation (alteration) affecting nerve cells in the cochlea, a sound-transmitting structure of the inner ear. The same genetic defect also adversely affects photoreceptor cells in the retina, leading to vision loss. The retina is a delicate tissue in the back of the eye composed of light-sensing photoreceptor cells. These cells — also known as rods and cones — are responsible for converting light into electrical impulses that transfer messages to the brain.

How is Usher syndrome inherited?


Usher syndrome is passed from parents to their offspring through an autosomal recessive inheritance pattern. In this type of inheritance, two copies of a mutated gene, one from each parent, are required for the child to be affected. A person with only one copy of the gene is a “carrier” and rarely has any symptoms. Genetic counselors are excellent resources for discussing inheritability, family planning, genetic testing, and other related issues.

Researchers estimate that as many as 50,000 people in the U.S. have Usher syndrome. Worldwide, it is the leading cause of combined deafness and blindness. Approximately 30 percent of people with RP report some degree of hearing loss, and about half of them are diagnosed with Usher syndrome. Genetic testing is becoming available to help people define their condition and the risk of other family members or future offspring being affected.

What treatments are available?

While there are no treatments for Usher syndrome, intensive research is underway to discover the causes of, and treatments for, all types of the disease.

Researchers have found numerous genetic variations causing Usher syndrome, allowing for the designation of a variety of subtypes (i.e., 1A, 1B, IC, 1D, 1E, 1F, 1G, 2A, 2B, 2C and 3A). Gene therapy to replace defective Usher genes is being studied in preclinical settings.

Researchers have also identified a nutritional therapy to slow the rate of vision loss in some RP patients. Although not a cure, they found that vitamin A palmitate can slow retinal degeneration in some people with RP and Usher syndrome type 2. They also showed that docosahexaenoic acid (DHA) — an omega-3 fatty acid — can enhance the effect of vitamin A. However, the enhanced benefit of DHA was realized only during the first two years of vitamin A therapy. (Only adult RP and USH2 patients were studied, so the effect in other patients with Ushers Syndrome is not known.)

In addition to nutritional therapies, researchers are working toward a variety of potential treatments for Usher syndrome, including artificial retinal implants, gene therapy and stem cell treatments.

For more information on research and clinical trials for Usher syndrome, refer to the Foundation publication Usher Syndrome: Research Advances.

Are there any related diseases?

Other conditions, some of which are also inherited, can result in deafness and deaf-blindness, but are not related to Usher syndrome. However, the RP associated with Usher syndrome shares most of its characteristics with other forms of RP. Researchers expect that advances in understanding and treating other forms of RP will directly benefit people with Usher syndrome, and vice versa.   

 

Back to top

US Images

Chapters

Select a state from the dropdown below to view local chapters.


Free Information

Register here to receive free information about your eye condition and research efforts to find treatments and cures.

VISIONS 2014 banner
2013 Annual Report banner
VisionWalk banner
Events Calendar