Researchers Recommend Update to AREDS Formula for Reducing Advanced AMD Risk

Results from a clinical trial known as the Age-Related Eye Disease Study 2 (AREDS2), conducted by the National Eye Institute (NEI), have led researchers to recommend updating the formula for reducing risk of advanced age-related macular degeneration (AMD). The first AREDS called for using beta carotene, but now researchers believe that lutein and zeaxanthin appear to be more effective in reducing risk of the disease. In addition, beta carotene was linked to higher rates of lung cancer for current and former

Self-Regenerating Retina One of Six New FFB-Funded Research Efforts

An emerging therapy to restore vision caused by retinal diseases—or potentially traumatic injury—is one of six new research projects being funded by the Foundation Fighting Blindness. The research effort is being led by Tom Reh, Ph.D., at the University of Washington. He’s investigating how Muller glia—cells that provide the retina with structural support—can be manipulated to also

Enhanced Imaging Technique May Help Identify Clinical Trial Participants

Just because a photoreceptor has stopped working due to the effects of a retinal degenerative disease doesn’t mean it’s forever lost. In fact, as the Foundation reported previously, José Sahel, M.D., a researcher at the Institut de la Vision in Paris, is developing a treatment to reactivate cones which have lost their light-sensing, antenna-like projections known as outer segments, but still retain their cell bodies, or inner segments.

Louisiana Family Helps Lead to Discovery of New RP Gene

A new gene linked to autosomal dominant retinitis pigmentosa (adRP) has been identified, thanks to a Foundation Fighting Blindness-funded genetic study that began with an Acadian family from Louisiana whose vision loss can be traced back to the early 1800s. Led by Stephen Daiger, Ph.D., at the University of Texas Health Science Center in Houston, an international research collaborative found that mutations in the gene HK1 cause

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