Gray font color on white background Black font color on white background White font color on black background White font color on dark blue background
Font Size
She really loves to suck cock and I love to film her sucking my penis This horny wife gives a blowjob licking the shaft of her husbands hard cock and then taking into her mouth Vegetables are healthy you know? My pussy is realy hungry and wants something inside I dildo the fuck out of my wet pussy thinking of how much cum my boss has filled me with Steaming hot hardcore porn videos turned on brunette babe with massive boobs in fishnet stocking home porn videos and high heels fingers her tight wet honey pot She earned every drop of my cum she give the best sloppy ameteur anal head ever sucking black cock This chick felt both our crotches back in the club office porn she knew she was in for a fun night She said she craved black cock and wanted to walk funny next day This horny husband finds his wife ironing in the porn tube kitchen and puts her down on the floor and fucks her doggystyle Young in love couple making homemade ebony sex porn letting him lick her out and insert himself deep and hard Flashing my sexy thong up my skirt porn stars then get cock stuffed up my cunt mature amateur sex movie This cock hungry brunette milf sucks on hard cock and then gets her mobile porn face covered with cum and her mouth filled up too as a bonus Seksi dekolte kiyafetli Macar kizlar yakin arkadasi ile evde porno hikaye sIkisme doyumsuz sex arzulari sinirsiz yasayip porno duskunu adami doyurma Japon ciplak porno hatun dar gotten yemis cilginca inliyor yarrak kicina girdigi goguslu sicak doyumsuz kiz ask yasamak erotik hikayeler sirada en cok zevk aldigi video ile gosterimi pornoda izle.
Foundation News » Retinitis Pigmentosa
PDF Print E-mail Bookmark Share This Page

Gene Therapy Reactivates Retina, Restores Vision

An international research team, funded in part by the Foundation Fighting Blindness, has used gene therapy to reactivate retinal cells that were previously unresponsive to light. The treatment was delivered to cones, the retinal cells that provide central and daytime vision. Investigators evaluated the gene therapy in two mouse models of retinal degenerative disease, as well as cultures of human retinal tissue. Using a variety of tests, the researchers demonstrated that the treated cells restored functional vision, and that the restoration of vision persisted over a long period of time.

In retinal degenerative diseases such as retinitis pigmentosa, cones stop providing vision before they die and can remain in a compromised state for several years. The gene therapy used to restore vision in the cone-reactivation study leads to the production of a light-sensitive protein called halorhodopsin, which is similar to vision-activating proteins occurring naturally in the retina. The presence of halorhodopsin appears to reactivate the visual cycle, the biochemical process in retinal cells that lead to vision.

An adeno-associated virus (AAV), a therapeutic virus, was used to deliver the treatment to the cones. AAVs are the same delivery mechanism used in landmark gene therapy clinical trials that have restored vision in 28 children and young adults who were virtually blind from Leber congenital amaurosis.

Dr. José-Alain Sahel, one of the cone-reactivation study investigators and director of the Foundation-funded Paris Research Center for the Study of Retina Degenerative Diseases, says that through high-resolution imaging, his team has identified people who may be good candidates for a future clinical trial. He adds that even people who are legally blind might have some cones reactivated and vision restored.

Dr. Sahel also notes that the cone-reactivation treatment has the potential to be even more beneficial if coupled with a therapy that helps protect cones from degeneration. Dr. Sahel and his team are planning a clinical trial of a neuroprotective treatment called rod-derived cone viability factor, or RdCVF, which has shown excellent results for preserving cones in preclinical studies.

The cone-reactivation study was led by Dr. Botond Roska of the Friedrich Miescher Institute for Biomedical Research in Switzerland, and included scientists from several European research institutions. Results of the study were published in the June 24 issue of the journal Science (online edition).


Back to top

US Images


Select a state from the dropdown below to view local chapters.

Free Information

Register here to receive free information about your eye condition and research efforts to find treatments and cures.

VISIONS 2014 banner
2013 Annual Report banner
VisionWalk banner
Events Calendar