About Us » FFB Funded Researchers
John Crabb, PhD
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John Crabb, PhD joined the Cleveland Clinic Foundation in 1998 as a full staff member in the Department of Ophthalmic Research, Cole Eye Institute with a secondary appointment in the Department of Cell Biology, Lerner Research Institute. He is a full faculty member and professor in the Department of Chemistry, Case Western Reserve University and in the Departments of Ophthalmology and Molecular Medicine in the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. He holds adjunct professorships in the Department of Chemistry, Cleveland State University and in the School of Biomedical Sciences, Kent State University. A major focus of his research concerns age-related macular degeneration (AMD). Proteomic biomarker studies are directed toward developing a blood test for AMD to identify those at risk prior to clinical evidence of the disease. Other proteomic studies in his laboratory focus on glaucoma biomarker discovery and the molecular details of the retinoid visual cycle. Information about the laboratory can be found on line at: www.lerner.ccf.org/eye/crabb/. Dr. Crabb received a bachelor's degree in biology and chemistry from Lewis & Clark College in Portland, OR, and a doctorate in microbiology from the University of Kansas Medical Center, Kansas City, KS. He pursued post-doctoral training in biological chemistry at the University of Michigan and in the biochemistry of vision at the University of Washington. Prior to joining the Cole Eye Institute, he was a senior scientist and the director of protein chemistry at the Adirondack Biomedical Research Institute in Lake Placid, N.Y. During the 14 years he was in upstate New York, Dr. Crabb maintained adjunct faculty appointments at the University of Vermont, Clarkson University and Albany Medical College. Prior to New York, he was an assistant professor and Director of the Protein Sequencing Facility in the Institute of Physiological Chemistry, Ruhr University, Bochum, Germany. Dr. Crabb has served full 5 year terms on NSF and NIH grant review panels and is a member of the editorial boards of Experimental Eye Research and the Journal of Ocular Biology, Disease and Informatics. He has published more than 190 basic science research articles and currently has research support from government, private and corporate sources. |
