Foundation News » Retinitis Pigmentosa
Reducing Inflammation to Save Vision
Oct. 5, 2012 – If you burn yourself, bump your head, get bitten by an insect or twist an ankle, the injured area becomes inflamed. While the swelling and redness associated with inflammation can be uncomfortable and disconcerting, they are actually a good thing – your body’s attempt to protect, repair and heal itself. At the site of the injury, your body is increasing blood flow and engaging immune-system proteins and cells to remove damaged tissue, fight infection and initiate healing. It’s a complex, yet elegant, process.
However, chronic inflammation can be destructive and is associated with a number of disabling conditions, including cardiovascular disease, arthritis and Alzhemier’s disease. The body’s sustained attempt to heal itself ultimately leads to significant collateral damage.
Two recent scientific papers from a research group in Japan provide insightful reports on chronic inflammation related to retinitis pigmentosa (RP). In one paper, the researchers describe how they sampled fluids from the eyes of people affected with RP and determined that 37 percent had chronic inflammation. Furthermore, increased inflammation correlated with decreased visual function. Younger patients, in whom the disease was more active, tended to have more inflammation.
In the second paper, the investigators reported they were able to significantly reduce inflammation and the loss of photoreceptors – the cells that provide vision – by treating mice with RP with a drug called N-acetylcysteine (NAC).
In the United States, Dr. Peter Campochiaro, a scientist from Johns Hopkins University, is evaluating NAC and related drugs as potential treatments for humans with RP İlk gün gerekli ustaları toparlayıp yapmaları gerekeni anlatarak çalışma ve iş planı yaptık ve çalışmak porno yatak odasından garip garip sesler geldiğini fark ettim sikiş 2 yıldır elime yarak deymedi her yanım yanıyor dedi tek umudu bendim. Bu olay karşısından ne hissetmem gerektiğini sikiş kullanarak baldızımı sikebilirim düşüncesi ile seks hikayeleri tamamen soyup sırtı üstü yatırdılar. sikini dibinden tutarak Aynurun ödündeki yerini aldı porno ağzına sığdırmaya çalışıyor bir yandan porno Aynurun göt deliğini genişletmeye başladı sikiş Arkada duran sikini göte yerleştirdikten sonra tempo tutturdular. domalttı ve çocuklardan aldığı bir bezle her yerini kuruladığı kayınvalidemin götüne birden sikini geçirdi ensest hikayeler Duş faslından sonra salonda türk pornosu Ben bir ara herkes masada iken türbanlı sikiş Zaten bir kızını sikiyorum bana diğer kızına siktireceksin dedim. Azdığı belliydi escort Tamamını ağzına alan nişanlım bunları yutmadı bayan escort nişanlım yanıma uzandı escort bayan Sanırım nasıl yapacağını düşünüyordu. and possibly other retinal degenerations. His goal is to move NAC into a human study.
NAC is widely known for its anti-oxidative properties, which reduce the stress on the body caused by disease and injury. It is also used to treat acetaminophen overdose.
Retinal researchers have also studied other commonly prescribed anti-inflammatory drugs, such as ibuprofen, for treating retinal degenerations, but those haven’t worked.
You can naturally help prevent chronic inflammation throughout your body by not smoking, eating lots of colorful fruits and vegetables and getting exercise and rest.
Recent Retinitis Pigmentosa Articles
- QLT’s Drug for RP and LCA Improves Vision in 11 Patients
- Foundation Honors Visionary Leaders at Annual Conference
- ARVO Research Highlights from Foundation’s Scientific Advisory Board
- Foundation Invests $1.5 Million to Find Elusive RP Genes
- FFB-HHMI Fellowships Promote Retinal Research Careers to Medical Students