Listen to this page using ReadSpeaker

UCI Stem Cell Pioneer Poised to Launch Clinical Trial for RP Patients

Dr. Henry Klassen, a Foundation-funded researcherHenry Klassen, M.D., Ph.D., is only about a year from launching a clinical trial for a stem cell treatment to rescue vision in people with retinitis pigmentosa (RP) and, potentially, other retinal diseases. At the Foundation’s recent Orange County Innovation Symposium, the University of California (UC), Irvine clinician-researcher reported that he and his colleagues are in the midst of final lab studies with patient-grade cells. Once finished, they’ll request authorization from the U.S. Food and Drug Administration to begin their human study.

But Dr. Klassen’s 35-year research journey to this pivotal moment was by no means conventional, nor was it embraced by many of his peers.

“During medical school at the University of Pittsburgh in the late ’80s, they thought I was crazy for getting a Ph.D. in addition to an M.D.,” he says. “That’s because, with a medical degree, there was nothing standing between me and an excellent income.”

He received similar criticism when he went from Yale, where he did his residency, to Moorfields Eye Hospital in England for a post-graduate fellowship. He passed on becoming a high-paying retinal surgeon because “the need for doing more research was reinforced when I saw the retinal degeneration patients,” he recalls. “The diagnosis was a grim message to have to deliver. I decided to concentrate on the research and come back to the clinic when I had something more to offer to patients.”

It was in the lab of Ray Lund, Ph.D. — a leading cell-therapy innovator who’s received Foundation funding — where Dr. Klassen first saw the potential for cell transplantation to restore vision. “When I got to Pittsburgh, I learned that Ray was doing retinal transplants and had showed that retinal grafts transplanted into the brain survived, and there was some integration,” he says. “That really thrilled me, so I joined his lab.”

Those early retinal graft experiments — before stem cells could be made into retinal cells — were technically difficult and tough to translate to humans. But they showed that transplanted retinal cells could connect to host neural tissue. Most important, they laid the groundwork for future retinal transplantation strategies, including those using stem cells.

In the 1990s, in collaborations with Dr. Lund and Michael Young, Ph.D., who was then at M.I.T., Dr. Klassen began making game-changing advancements in transplanting retinal cells into the eyes of rats with retinal degenerations. “As I’m looking through this microscope, I’m seeing something I never expected — a transplanted cell that could migrate through adult neural tissue and find its way to the right spot, park and start extending new connections into the host circuitry,” he remembers. “It was amazing. It was the breakthrough I’d been looking for.”

That was also about the time when he received a Career Development Award from the Foundation, to help advance his research. “I had seen a flier from the FFB when it was known as the RP Foundation. It was exciting to find an organization that was doing exactly what I wanted to do,” says Dr. Klassen.

Today, stem cell research for retinal diseases is blossoming, with several clinical trials planned or underway. Dr. Lund’s work led to the 2011 launch of Advanced Cell Technology’s human trial of a stem-cell-derived therapy for people with age-related macular degeneration and Stargardt disease. With support from the Foundation, Dr. Young is helping the company ReNeuron prepare for a stem cell clinical trial for people with RP scheduled to begin by early 2015. Both ReNeuron’s and ACT’s therapies involve injections of cells underneath the retina to replace those cells lost to disease.

Dr. Klassen’s forthcoming clinical study involves the injection of retinal progenitors — stem cells that have partially developed into retinal cells — into the patient’s vitreous, where they’ll release factors to preserve and rescue existing retinal tissue. He says that a benefit of his approach is that it doesn’t involve a more invasive subretinal procedure, which would be required if lost cells were being replaced. Also, his progenitor-based therapy has the potential to rescue a variety of retinal cells — including rods, cones, retinal pigment epithelium and ganglion cells — and, therefore, may save vision in people with a wide range of conditions.

After decades in the field, Dr. Klassen acknowledges that reaching this promising juncture wasn’t easy. “I have seen a lot of ups and downs with these technologies. It wasn’t like somebody invented one thing in their garage and everything was solved,” he says. “Finally, we are getting to the point where stem cells are poised to do something meaningful in the clinic.”

Pictured, above: Henry Klassen, M.D., Ph.D. 


102 Responses to 'UCI Stem Cell Pioneer Poised to Launch Clinical Trial for RP Patients'

  1. Marisa says:

    Dear Sirs,
    We are interested in your study. What shall we do to enrol?
    Thank you very much.
    Marisa

    • Diana Durbin says:

      Please enroll Me Please God Bless You
      Diana Durbin

    • Mike Martin says:

      My wife and mother both suffer from RP. Please send me any more info you have. My wife would love to be part of your clinical trials. Please let us now how to be part of it.

  2. Lizzette Hernandez says:

    Hello ,

    My husband and I are very interested in your study , pls let us know what can we do to be part of it …

    Thank you

  3. Nydia Mendez says:

    My granddaughter, Nydia Mendez, has had R.P. for twenty years and she is losing her right eye and the left eye is following. She lives in Camarillo, California and would probably be very interested in being a part of the stem cell clinical trial next year. Could you please send her information. Thanks.

    • EyeOnTheCure says:

      Nydia, We would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  4. Kris says:

    As a person with rp I thank you for your hard work and studies on this terrible disease. Hope to see you in the future with the cure.

  5. umesh kumar agarwal says:

    wonderful hope for children and teenagers specially may god bless you and enlighten you more for the cause of humanity. thanx. umesh kumar agarwal, india, darjeeling

  6. Henry Bui says:

    Hi,

    I am a young university graduate who is entering into a pivotal part of my career and my life. My biggest set-back is having retinitis pigmentosa. It has greatly effected mine and my two brothers’ everyday quality of life (they also suffer from it). I would like to inquire more about these trials and hopefully be a part of it.

    Thank you so much for your time and contribution to the study.

    Henry Bui

    • EyeOnTheCure says:

      Henry, we would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for RP clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  7. Scott says:

    We are interested in your study. What do we need to do to enroll?

    Thank you very much

    • EyeOnTheCure says:

      Scott, We would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

    • Brenda HUYNEN says:

      My son has Usher Syndrome. I would be so grateful to have him on the list for this trial

  8. sharon says:

    Question, are you working on a cure for rop My 14 teen year old daughter has it. You are all taking too long. I’m sorry but at this rate your at least 5 years away. I don’t understand why you can’t have more clinical trials on people who don’t have eyesight!!!!! There is nothing worst then not being able to see……… the children who live in the dark..

    • EyeOnTheCure says:

      Sharon,
      Unfortunately, ROP is not a disease that we specialize in funding research for. We would encourage you to check out the National Eye Institutes page on ROP. Towards the right of this page you will see a link for some information on organizations and institutes that focus on research and resources for ROP and those who suffer from it.

      http://www.nei.nih.gov/health/rop/index.asp

      Thank you.

    • Eric says:

      Telling them to “hurry up because they’re taking too long” is idiotic and completly greedy and rude. I myself have RP. And i would want nothing more then for there to be a cure so i can live my dream of being in the armed forces. But really? Based on your comment i can tell you have no level of Education about stem cell research. I work in a stemcell research lab for the University of PA and they work so hard everyday and all they think about is the millions they could be saving, it’s not as simply as “here lets just inject you with stem cells”

  9. Concetta Collemi says:

    This is such exciting news. My husband has RP and would love to be considered for this trial. Can you please forward me information once this is FDA approved. Thanks for all of your hard work!!!

  10. Jenny Dennis says:

    I have 5 degrees left in both eyes due to RP. I have 4 children, play the piano, and really misses driving. I get hurt a lot by running into things. Please include me in the study.

  11. Carol Quesenberry says:

    I would be very interested in information re participation in this study. Thank you.

    Carol

    • EyeOnTheCure says:

      Carol,

      We would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  12. JS says:

    The article is very interesting, promising, and I would like to be considered as well for the upcoming human trial. Please advise on how one can participate. The only restriction for me right now is my vision restrictions via RP. Thank you.

    • EyeOnTheCure says:

      JS,

      We would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  13. Dan Merchant says:

    very promising hope for the people with vision defects Hope that the life long mission of Dr klassen
    succsed and bring light in the darkness

  14. Lee says:

    Our son in law suffers from RP and it limits his daily activities and as a new father has also put a greater strain on our daughter because he cannot drive. Would like more info on this study and how he can participate please

    • EyeOnTheCure says:

      Lee,

      We would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  15. Shilpi Mukherjee says:

    DEAR SIR
    PLEASE SEND ME MORE INFORMATION ON THIS.MY SISTER HAS RP AND WOULD LIKE TO KNOW IF SHE CAN TAKE PART IN THE TRIAL ETC.
    SHILPI

    • EyeOnTheCure says:

      Shilpi,

      We would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  16. Nick says:

    I’m interested in your clinical trial as I am 38 and have RP.
    Could you please contact me when you have more information.
    Thank you kindly.

    Nick.

    • EyeOnTheCure says:

      Nick,

      We would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  17. brenda says:

    I have rp terrible to know your gonna loose your eye sight iam very but very interested in your study thanks for restoring my hope for me n my kids what do i need to enroll.

  18. Charles says:

    Hey My Name is Charles Michael Turner im Am 18 years old and i will be turning 19 in august i was Diagnosed with RP when i was like 4-6 years old and ive always been scared of completely loseing my eye sight i have even cryed about it many many time because i fear the unknown and i would like to help by any means to help produce a cure for this Disease i attended L.S.V.I (Louisiana School For The Visually Impaired) for years and learned brail but i dropped out because of my eyes sight is pretty poor and i will never be able to operate a vehicle and it is my biggest dream to be able to get a drivers license i strugle alot trying to watch movies and play games and sometimes i have black outs to where im completely blind for 3-10 seconds and i get really light headed and it hurts i justy want to be able to get to 20/20 vision or at least be able to see well enough to drive i would really like to perticipate in this if you would let me my number is 774-634-7557 if you can contact me i would really appreciate it learning more about my eye deficiency and how to improve my vision please help me i would really be grateful

    • EyeOnTheCure says:

      Charles,

      We would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  19. sky seace says:

    I am very interested in taking part in the upcoming clinical trial for RP (stem cell) I have RP and am considered to be legally blind from it now. My mother is almost completely blind from RP as well.

    please consider me for your trials I am willing to travel and stay for as long as it takes for the trial.

    Thank you,
    Sky S

    • EyeOnTheCure says:

      Sky,
      We would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  20. claude daucet says:

    i have autosomal dominant retinaitis pigmenosis for the last 30 years and it increasingly getting worse. it is hereditary and i would very much like to be involved in your research study. I am very independent as i am building a garage but i would love to be able to see it and to quit hitting my thumb so much. lol (this is his friend Linda – you will never hear him complain and i try to help him as he stumbles. He is extremely ingelligent and works hard so people do not realize his disability. he is a very caring person who puts GOD first and truly loves the outdoors. Please allow him the opportunity to be in your study)

  21. Farah Rais says:

    I wish you the best of luck. What can we do to be part of this study?

    Thank you

    • EyeOnTheCure says:

      Farah,

      We would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  22. Ann Menegis says:

    My son is 21 years old and was diagnosed at age 4 with x linked retinal schizma.He lives a normal life but his poor vision does impact on day to day living. I believe there is no treatment available for him,but after reading your article on stem cell therapy wondered if there is any hope that it would help him in future?I think your research is just tremendous and has such a potential for really changing lives.

  23. Steven D. says:

    Thank you so very much for your spirited efforts. I lost the final shred of my eyesight to recessive RP some years ago, and have been reduced to a bit of mere light perception in both eyes; I was once an avid Astronomer & Yachtsman. From time to time I find myself touching my telescope or longing for the Sea, and nearly bursting into tears as I’m beginning to forget the wonders I once witnessed so many years ago. I keep moving forward, and am now preparing to enter Law School so that I may continue to do something meaningful with my life. If participating in your trial could return me to the world I once knew, I would appreciate the opportunity to do so.

    Ever travelling upon the level…

  24. Layla Wadrassi says:

    Hi

    I am 32 years old and have been told that I have RP. I fid it very difficult in bright conditions and I have had to give up driving. I am finding it very difficult to come to terms with the fact that I will los my sight as I have a daughter who I would very much like to see grow up. I like most of those that have commented miss being able to drive. I would like to thank you and your colleagues for your persistent hard work and research. You have given me hope and I am deeply grateful.

    Thank You
    Layla

  25. Greg Pearce says:

    Dr.Klassen.Hello my name Is Greg Pearce and my son Nathan has rp due to bardet biedl syndrome we live in fresno ca and I would love to get more info of your up coming study.Nathan is 14 and my daughter is 15 months and also has bbs.there defect is on the bbs1 gene.I don’t know if kids are allowed in your study or not but it would be a true blessing if they are.Im just a dad doing whatever I can to help my kids I tell my son to never give up that god will come through.i see god working through you and fellow researchers like you,may god bless all of your hardwork and thanks for all you do.

  26. Elisangela Vinagre says:

    Hi,
    I have a nephew that since he was born he had vision problems, and now he is 34 years old with just almost with no vision at all. As i was reading about your study i would like to know more about it if anyone can get back to me. Thank you
    Elisangela Vinagre

    • EyeOnTheCure says:

      Thanks for your comment Elisangela. Are you interested in being a volunteer for a clinical trial study?

      If so, we would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  27. Lauren says:

    My sister and I both have RP and would be interested and participating in the study. Please let us know when it is approved and what we need to do to enroll. Thank you.
    Lauren

  28. Vinay G says:

    I just came across this article. I have been regularly keeping up with FFB, but somehow missed this article. I have RP for quite some time now and am interested in participating in your clinical trials, if I qualify. Please include me and let me know. Thank you and God Bless!

    - Vinay

  29. Victoria says:

    My father has had RP my entire life. Both me and my sister were tested regularly since we were young to see if we also had RP. My father did not loose the majority of his eye sight until my senior year in high school. Right now he can only see light and shadows. I am not sure what the qualifications are for your clinical trial but I know that my father has been hopeful for a possible cure for RP. He has talked regularly about hearing about other blind people being apart of research and being able to see for various reasons. If you could please email me with the details of your trial and let me know what the qualifications are.

    • EyeOnTheCure says:

      Victoria, we would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  30. My sister(48 yrs old) and my brother (53 yrs old)both have RP. They are both interested in participating in Dr. Klassen’s RP clinical trail. Please contact me at the above email address. Thank You, Talita

  31. soma patnaik says:

    thanks for ur research work.let me know if can transplant my retina.i have rp.

  32. Grace says:

    Im so truly grateful for this research! Im 37 diagnosed with RP over 10 years ago.
    Loosing my eyesight gradually.
    Would like more information.
    Thank you for working so hard to find a cure to our eyes!

  33. Aleida Neira says:

    Hello Dr Klassen
    My three daughters 26, 22, 22 have RA, and very high myopia and astigmatism, we are very interest in the study.

  34. vicky says:

    hello, my name is Vicky, first of all, i want to thank Dr. Klassen and all of the other researchers that has dedicated there life to find a cure for blindness. I truly believe that god is working through you all. I am 51 years old and I have RP. unfortunately, RP has effected many of my family members, at least 18 or so family members. my son mother, brother, nieces, grandparents, two aunts, an uncle, and many, many cousins have struggled with the effects of R.P. I have ALWAYS BELIEVED that researchers would find a cure for R.P. I want to know more about this clinical trial for R.P. . I would love to be a part of the research that would possibly help so many of my family members to have a better life . Pease contact me concerning this trial study. THANK YOU SO MUCH FOR THIS HOPE!!

    • Paul H. says:

      Hi
      First thank you for all your work.

      My Daughter has RP and is down to circa 10 degrees in both her eyes. She tries not to let it effect what she does .

      We live in the UK and attend Morefields yearly. My wife / her mother is a GP.

      Please advise if it is possible to become involved with the trial.

      Many thanks and best of luck!

      Paul

  35. Ripen says:

    Hi Doctor.

    If you could succeed, you will be a god to many unfortunates like us. Just few days back my daughter was diagnosed with USHF1, which may lead to RP. She is noraml now and we donot know, how progressive it would be in future. Will be waiting for your announcement.

    All the best.

  36. Vijay Sethi says:

    Dear Dr. Klassen ,You are doing wonderful work for millions of people suffering from RP. I am from India, near New Delhi. My wife and her three siblings are suffering from RP and I am not sure about my children eyes condition who are ten and six years old. My wife is 39 years old and she is suffering from RP from last ten years. Her vision is getting deteriorated very rapidly in last two years. Can she be part of your clinical trial that I do not know, but surely if it is possible, we would like to part of it.

  37. Heather says:

    I am very interested in your trial, I suffer from severe RP and would be very interested in participating.

  38. Lynn Lyons says:

    Please send me information on how I can get involved in a clinical trial. I am quickly losing my eyesight to retinitis pigmintosa and would do anything to stop its progression. I am fifty four years old and have so much more I want to see. God bless you for your work in this area. I have had to watch my Dad lose his sight to this horrible disease and I recently found out that my son has it as well. My heart is broken for both. Please consider me as a canidate for any clinical trial you may have going on now or in the future. Thank you Dr. Klassen for your dedication to this disease.

    • EyeOnTheCure says:

      Lynn, we would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  39. Jemond Smith says:

    Hi, my son was diagnosed with RP at 5 years old and is now 7. His uncle (his mothers brother) was also diagnosed with this condition at birth and is now 24 years old. It wasn’t until my son was diagnosed that we found out this is a condition that is genetically inherited, however we now have two sons. The youngest is 3 years old and we have not had him checked to see if he has RP. Our oldest son is currently getting checked annually by a specialist who’s a part of Baylor Medical Center and is on a board primarily focused on this condition.

    Please advise if there’s something we can do to have our son participate in your clinical study.

    Thanks for your dedication to find a cure for this condition!

    • EyeOnTheCure says:

      Jemond, we would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  40. Rubi says:

    My 36 year old husband and
    father-in-law both suffer from RP . My husband was diagnosed at a very young age and would want to be part this clinical trial. Please inform us with what to do..
    Thank you for your extensive dedication to finding a cure for RP.

  41. mahtab says:

    Hi
    i am 26 years old. i have retinitis pigmentosa. my peripheral vision has been destroyed. i have a central vision. Im suffering from this disease. i sent my medical reports for you.
    Thank you for your extensive dedication to finding a cure for RP.

  42. K.Prakash Rao says:

    Hi,the outcome is quite thrilling.Hats up to u.My son is having low vision due to retinal defect with high myopia.The news has kindled a ray of hope.Let the almighty help u in achieving the goal so that crores of people can see the wold.
    Ready to participate in ur noble work

  43. Michael says:

    Fantastic to see such progress in the world of RP.

    I’d love to find out more and also learn what I can be doing today to best position myself in the future for an appropriate trial.

    I have RP, currently being tested for Ushers Syndrome, and am based in New York but can get to London easily. Whilst regaining pheriphal vision would be amazing, just restoring my night vision would be life changing in itself.

    Would also love to learn more on how I can help.

    Thanks for your time and keep up the great work!
    Michael. M

  44. Santiago Rivoir says:

    My father was diagnosed with RP almost 50 years ago, rate now his vision is very limited, what do i need to do to enroll on this clinical trial.
    Thanks for all you are doing!!!

    • EyeOnTheCure says:

      Santiago, we would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  45. God bless and god speed to you and your research team.

  46. Dee says:

    Thank you so much for all your research and I hope that there is a cure
    Very soon . I don’t want any more eyesight to
    Be lost . My brother has RP and I know that he wants to
    Participate in your study before any more sight is lost . He is 42 years old.
    Please contact me with any further details , thank you

  47. Dan Hultstrand says:

    Hi!
    My son has a disease callesd Sticklers syndrome and has had retinal detachement leading to one eye being blind and the other has recently had two retinal detachements, but he still sees on one eye. Please let me know if there is somewhere preferebly in Europe that can use retinal stem cell treatment now or in the future that i can contact for help and treatmant.
    Kind regards Dan

  48. Edwin Tobia says:

    Hello Sir,

    I have 9 year old daughter suffering RP and would like to here more and possibly participate in the your study. This is best possible news ever if you pull through and would be a miracle gift for my daughter to improve her vision condition.

    Thank you.

  49. Earl Dockstader says:

    My wife is writing this out for me because I have RP, and have had it since 1955 when it was discovered. My Uncle had it but there wasn’t even a name for it when he went blind @ the age of 35. I wasn’t diagnosed with it until they could figure out what it was, I was in and out of Children’s Hospital in Los Angeles while they tried to figure out what I had. Now into my 70′s and I’ve never been able to drive a car but have taught others how to drive a manuel transmission just by listening to the gears you can tell when it’s time to shift. My nephew also has this same diagnoses since he was a kid now he’s grown & has children everyone is @ risk in our family my sister passed it to her son, & it just keeps on going. I would love to be a part of your study, this disease has been in my family for over 100 years, I’d sure love to nip it in the bud.

    Thank you
    Earl & Cheryl Dockstader

  50. Lyndia Tucker says:

    At 63 years old, I’ve had RP for a long time. With vision limited to 3 degrees, light and shadowy shapes, I’m still very independent, cook, clean my house for my husband after retiring from a varied career. We have 3 children, and 6 grandchildren, who do not appear to have RP. I think a poor childhood diet increases the severity of RP, as my diet was very low in foods with vitamin A and C. Nontheless, I am very thankful for your hard work and dedicated research and would like to get information on how to participate in your stemcell trials. Thanks, and Godspeed your work. the

  51. Cheryl Playter says:

    I am very interested in participating in this trial. I am a single mom of 3 kids, I was diagnosed 9 years ago. Please let me know what I need to do.
    Thank you for your dedication to finding a cure for RP.

  52. Ramin Nikpour says:

    I am very exciting right now.Thanks for your effort. I hope you quickly get better results in human.I am also suffering RP and would like to be part of your study.I live in Iran and there is no limit to travel anywhere you tell. Please help us in this case. I lose my right eye’s vision and my left also following the right one.
    Yours sincerely
    Best Regards

  53. john says:

    my brother and sister both in there 40s have RP they are 8 years apart; if they could participate in your trial it would be great thanks

  54. Beth Prather says:

    My twin sister and I both suffer from retina pigmentosa for over 20 years. It has greatly affected our lives as the easiest tasks in life became very difficult. We are in our late 40′s and our dream is to live the second half of our lives with a fuller life (mainly restore our lost vision.) It is very difficult not to enjoy life to the fullest, not being able to drive at night, see things, injure ourselves walking into things because the peripheral vision is affected. We would love to find out how we can participate in the future stem cell therapy. Please contact me when these trials will be offered. We both live in Illinois but would travel anywhere if hope is there.

    Thank you.

  55. Julie turner says:

    Great to hear what you are doing. My three year old has RP and we are desperate to help her. We can hardly wait to know how the trials go, as would be delighted to help in any way we can. Regards, Julie

  56. Hunter Lawrence says:

    HI, my name is Hunter, and I have RP. I am graduating this year from high school and will be gong to college next fall. I am very scared of losing my vision completely, right now i can hardly see out of my right eye and it isn’t much better in my left. Like many people on here I struggle in the dark and when it seems like my friends can see fine i walk into everything. I would be willing to do anything possible to try to get my vision back, and have a chance at living a normal life. Thank you for all of your work and please let me know what it takes to be a part of the study.

    • EyeOnTheCure says:

      Hunter, we would recommend that you visit http://www.ClinicalTrials.gov. We fund many clinical trials but do not operate the studies ourselves and so reaching out them directly may be the best way for you to find out more about where they are happening and if participating is an option.

      On twww.ClinicalTrials.gov, which is maintained by the National Health Institute, you are able to search for clinical trials by searching based on your disease. Each clinical trial listing will tell you more about what the study is about and how you can contact them to see if they are recruiting and what the participant criteria may be.

      We hope this information is helpful and encourage you to contact us for additional help at info@fightblindness.org for further information if needed.

  57. Kishor says:

    My wife has RP. This article was forwarded by her brother who also has RP. Would be interested in the clinical trial.Wishing you the best in your research so that many people could have more vision.

  58. Mona nori says:

    I have 13 years old daughter , she diagnosed with rp 11 years ago ,her vision decreased alot last year , we are interest in this clinical trial

  59. Kristen Keightley says:

    Fantastic news! I was diagnosed only 3 days ago and I’m 30yrs of age. Going by family history it is the AD form of RP. My mother has it, her father had it and his mother had it, along with various cousins/ uncles /aunts. Although mine is only mild at this stage, I have two children under the age of two in which I would do anything to watch my girls grow up. I am trying to be positive as alot of those who do or did have rp kept their central vision. My mother is close to 50yrs old and is still driving and getting around on her own. However she has her bad days which restrict her peripheral vision. Please keep me informed and up to date with these trials. I’m a true believer that all things are possible and I pray that you have found the answer that so many people are looking for.

  60. Aran Nanor says:

    Dear Dr. Klassen ,You are doing wonderful work for millions of people suffering from RP.

    I am 53 years old and been diagnose with RP few years ago. as an athlete I had to gave up different type of sports and those I can do must be on a day time only.
    I am living in LA. California. I will be happy to take part of your clinical trial.
    Thank you Aran

  61. Peter Bush says:

    My wife and daughter suffer from this disease. My wife has had it for 30years and we would love to be kept informed and if possible a part of the trials. We live in Australia. We pray that you will make rapid successful progress with this treatment.

  62. Timothy says:

    My identical twin brother and I are 54 and have both lost our vision to RP. Can this therapy restore vision that has already been lost? Please tell us how we can participate in the human trials in 2015? Thank you. God’s abundant blessings. Tim

  63. Morteza Shahbazinia says:

    I am 45 years old associate prof. of law and been diagnose with RP and cataract few years ago. doctors said, thay can not operate my cataract because there is a risk that surgery to result in blindness.is this correct?

  64. Doug Cowen says:

    I was diagnosed with RP in 1983 at the age of 23. I am now 54 years old. It’s been a long tough journey but I can still see even though the vision that I have is impaired. I have the opposite of tunnel vision. I believe it’s called “Rod to Cone RP.” Even though most of my central vision is gone, I’m still able to function quite well due to some peripheral vision that has remained in tact. In any case my heart goes out to everyone on this page who is looking and hoping for a cure. Like so many of them, I am interested in the clinical trial (study) as well. I would welcome the opportunity to learn more about this. Thanks for your time and best regards. Doug Cowen

  65. Rekha Ramesh says:

    Hi Dr. Klassen,

    First, it is great to hear about your work which gives hope for so many patients suffering with out cure.

    My brother suffers from RP (he might be having Lawrence moon syndrome). He is 38 years old. Recently his vision has deteriorated. He is almost completely blind now. He is a strong individual who managed to finish his masters in commerce and has his own small home business, but recently he is restricting himself from going out and has lost his confidence. He lives in India.

    It will really be beneficial for him to be part of the trial. Greatly appreciate the opportunity. Looking forward to hearing back from you

    Wish you the very best. Rekha

  66. Debra Thompson says:

    My husband has been diagnosed with RP and the doctor said he is legally blind. His mother went totally blind from this disease. We are very interested in joining in with the trial process as he is only 48 years old and has always been a hard worker. He has been depressed to learn he can no longer work or may not be able to see our precious grand babies in the future. PLEASE HELP and THANKS for all you have done in the research!!
    Debbie Thompson

  67. Paul Bailey says:

    Dr. Klassen, my wife Lyn Bailey suffers from RP. Lyn is 59 years old, exercises regularly, and healthily approaches the world. We live on the Monterey Bay in Santa Cruz County. She would like for her to have the chance to be part of your study. Thank you, Paul

  68. Barbara Klein says:

    Hi Dr.Klassen, I am writing on behalf of my two sisters and one brother. we are extremely excited that you have made progress and hopefully a cure. my brother is completely blind one sister see shadows and the other very as long as the light is right. all three are very excited and extremely interested in participating in your trial group. please contact me and let me know how this can happen. I can’t tell you how much this would mean to all of us. may God bless you for all you for your commitment to this disease

  69. Dear Sir,
    I had undergone retinal eye surgery vitrectomy in the year 1993 in UK Manchester Royal Eye Hospital performed by Professor David McLeod. The retina of my left eye reattached by normal procedure and filled with silicon oil while my right eye treated by laser treatment as a precautionary measure and filled with air bubble as per professor it was due to Eule disease I am hypertion patient. The vision of my right eye is perfect only problem to see in night while my left eye vision is not cleared opaque and blurred objects appear tiny and very little light. In my case is there any hope for the restoration of my left eye vision. By profession I am an Engineer working in Saudi Electricity Company and due to my vision my job is on stake kindly help me in this regard. I shall be grateful to you.
    Thanks,

    Muhammad Junaid Abbasi,
    00-966 532215019 & 545034571

    • EyeOnTheCure says:

      You would best be served by contacting an ophthalmologist in the U.K. or in Saudi Arabia and have them evaluate your condition. Don’t wait until it gets worse.

  70. Dear Sir,
    I had undergone retinal eye surgery vitrectomy in the year 1993 in UK Manchester Royal Eye Hospital performed by Professor David McLeod. The retina of my left eye reattached by normal procedure and filled with silicon oil while my right eye treated by laser treatment as a precautionary measure and filled with air bubble I am hypertion patient and my age 58 years. The vision of my right eye is perfect only problem to see in night while my left eye vision is not cleared opaque and blurred objects appear tiny and very little light. In my case is there any hope for the restoration of my left eye vision. By profession I am an Engineer working in Saudi Electricity Company and due to my vision my job is on stake. I shall be grateful to you. Thanks, Muhammad Junaid Abbasi,
    00-966 532215019 & 545034571 -

  71. John A Coleman says:

    I hAVE LOST MOST OF VISION IN RIGHT EYE AND HAD VITRECTOMY JUST LAST WEEK. i WOULD LIKE TO BE PLACED ON WAITING LIST FOR CLINICAL TRIALS FOR POSSIBILITY TO REGAIN SOME OF VISION LOSS. GOD BLESS YOU
    THANK YOU,

    • EyeOnTheCure says:

      Thanks for your comment. The Foundation Fighting Blindness funds many clinical trials but does not manage the studies and so reaching out to them directly may be the best way for you to find out more about where they are happening and if participating is an option. The website: http://WWW.CLINICALTRIALS.GOV is maintained by the National Institutes of Health and contains a searchable list of clinical trials for most known diseases. Each clinical trial listing will provide you with information on what the study is about, the requirements for participating and contact information.

Leave a Reply

Your email address will not be published. Required fields are marked *

*