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The Retina Goes Bionic

Video Included
Bionic Eye GraphicRemember the 1970s TV show The Six Million Dollar Man, featuring Lee Majors as Col. Steve Austin? Also known as the “Bionic Man,” he had a number of bionic – electronic and/or mechanical – body parts, including one eye, which gave him super-human powers to fight evildoers and save pets, small children and damsels in distress from imminent peril.

I can still hear the opening voiceover of the show: “We can rebuild him. We have the technology. We can make him better than he was.” And I can’t forget the low-tech sound effect (ching-ching-ching) and slow-motion visuals whenever Austin performed one of his bionic feats. The show was a guilty pleasure I looked forward to every week.

But bionics is no longer just entertaining TV. And while today we can’t always make people better than they originally were, researchers are developing incredible bionic technology to improve the quality of life. The “bionic,” or artificial, retina is one such example.

Thanks to the company Second Sight, people who’ve lost their vision to retinitis pigmentosa can now buy an artificial retina in Europe; and the company is hoping to gain FDA approval soon to make it available in the U.S. Its device, called the Argus II, doesn’t have all the features of Steve Austin’s bionic eye, but it does provide rudimentary vision to people who are otherwise completely blind.

The video below, from this CBS News piece, features a user of the Argus II and Foundation-funded researcher Dr. Lucian del Priore, who demonstrates how the device works and the independence it can provide. Promising clinical trial results, which could be key to FDA approval of the device, will be published in April in the peer-reviewed journal Ophthalmology. In that paper, Second Sight will report that the Argus II consistently improved vision and worked safely.

More than a decade ago, FFB funded lab research at Johns Hopkins University for an early version of this technology, and it’s exciting to see it working in people today. (The juice was definitely worth the squeeze for the Foundation to invest in this). Dr. Brian Mech, vice president of development at Second Sight, recently told me that, in 2014, the company plans to launch a clinical trial of the Argus III, which has 240 electrodes, compared to the Argus II’s 60 electrodes. The increased number is expected to give the user sharper vision.

Other companies are developing artificial retina technology, including the German company Retina Implant AG, which has reported good results in early clinical studies – and will be at VISIONS 2012, FFB’s national conference, this summer in Minneapolis – as well as Nano Retina, in Israel, and Bionic Vision Australia.

I look forward to reporting on forthcoming advancements for these promising technologies – which have the potential to counteract vision loss caused by various retinal degenerations – as they occur.

As for the Six Million Dollar Man, Lee Majors is now 72 years old. And, adjusting for inflation, my guess is that he should now be referred to as the Thirty-Sixty Million Dollar Man.


8 Responses to 'The Retina Goes Bionic'

  1. Farshad says:

    Dr Rose,

    You are doing a great thing posting these blogs, I chek it everyday. My son has LCA, and i feel very hopeful one day there will be multiple options for his cure. Thank you

  2. RobertAZ says:

    The Argus II and the Optogenetics research and other genetic therapy research definitely give me and others hope for the somewhat near future for vision. It brings up the question; how will so many people be able to afford any of these techniques? I have health insurance threw a major insurance company now and they won’t even cover glucose test strips for my talking glucose monitor. I would be very surprised if my insurance would pay for any of these life changing vision restoration procedures. I don’t even know if volunteering for Clinical trials is totally paid for or not.
    With all the break-threws happening in medicine; I believe that the President’s Health Coverage plan; with room for improvement, gives everyone the, not just blind people the best chance of treatments that could dramatically improve our health in the future JMO. It is a real shame that many people in the World still go blind from mal-nutrition. In my Ideal World; good health would not depend on money.

  3. Amy says:

    As cool as bionics are – they aren’t a cure, they are a fix; a patch. Where is the cure? Stem cell research, please post about what the Foundation is doing in that area. Thank you.

  4. Wow that was odd. I just wrote an really long comment but after I clicked submit my comment didn’t appear. Grrrr… well I’m not writing all that over again. Regardless, just wanted to say fantastic blog!

  5. Ajay says:

    Will this be helpful for those who have suffered from Retinoblstoma?

    • EyeOnTheCure says:

      Thanks for your comment Ajay,

      The Argus II retinal prosthesis was developed for people with retinal degenerative diseases such as retinitis pigmentosa. At this point, it isn’t designed to help people with retinoblastoma, which is a cancer. That isn’t to say that a future artificial retina or prosthesis would not help someone with a retinoblastoma.

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