Listen to this page using ReadSpeaker
Posts tagged Dr. Don Zack

To Treat an Inherited Retinal Disease, It’s Good to Know Exactly What’s Wrong with the Gene

Jason Comander, M.D., Ph.D.In simple terms, genes are like recipes for making proteins. All the cells in our bodies “read” genetic information so they can make the critical proteins necessary to stay healthy and function properly. If there is a mistake in a gene — that is, a misspelling — a protein might not be made correctly and cells in the retina might degenerate and cause vision loss.

These misspellings are called mutations, and just like a mistake in a recipe, some mutations are more devastating than others. For example, when baking a cake, let’s say there is an error in the recipe. It incorrectly calls for a quarter cup of sugar, when the right amount is a half of a cup. The cake may not taste great, but it is still edible. But let’s say the instruction for adding flour is omitted entirely. Then the cake will be a complete failure and go uneaten.

Continue Reading…

New NIH Institute Accelerating Sight-Saving Research to the Clinic

NCATS at the NIH helps move retinal research projects toward clinical trials. When it comes to advancing potential sight-saving treatments into human studies, collaborations and partnerships are critical to accelerating the research process. That’s why fighting blindness has always been a team effort for us.
Continue Reading…