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Posts tagged arvo

Grow Your Own: Harnessing Muller Glia for Retinal Regeneration

As I wind down the week at the annual meeting of the Association for Research in Vision and Ophthalmology (ARVO), I’d like to introduce an intriguing therapeutic approach to retinal degeneration that would be a home run if perfected. It’s called retinal regeneration, and it happens to be right in line with the National Eye Institute’s life-changing audacious goal, announced on Monday: “to regenerate the neurons and neural connections in the eye and visual system.”
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ARVO Update on Optogenetics: New Light for People with Advanced Vision Loss

Keirnan Willett.One of the promising emerging approaches to restoring vision in people with advanced retinal diseases is a form of therapy known as optogenetics. In essence, this type of treatment restores light sensitivity — and, potentially, meaningful vision — to people who have very little, if any, vision remaining. An important benefit of optogenetics is that it should work regardless of the underlying genetic defect causing the disease. While it is too early to speculate how well optogenetics will ultimately work, we’re hoping it ends up retiring a lot of white canes. Continue Reading…

RP Gene Therapy Clinical Trial Update from ARVO

Drs. Nicola Ghazi (left) and Doug Vollrath. I am always pleased to hear reports on human studies for retinal diseases. And such is the case with a research poster I just reviewed at the Association for Research in Vision and Ophthalmology (ARVO) annual meeting. It described a new clinical trial underway for a potentially life-changing gene therapy for people with autosomal recessive retinitis pigmentosa (MERTK mutations) taking place at King Khaled Eye Specialist Hospital in Saudi Arabia.
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Retinal Regeneration is Major Focus of NEI’s Audacious Goal

Paul SieivingThe National Eye Institute (NEI) just announced that fighting blindness — retinal degenerations, in particular — has gotten audacious. It’s potentially life-changing news for people with these difficult conditions.
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Stay Tuned for Daily Updates on “Life-Changing Research” from ARVO

ARVO 2013 discuss some of the posters on displayI am excited to be reporting to you live from Seattle where about 10,000 of the world’s top eye researchers are convening for the annual meeting of the Association for Research in Vision and Ophthalmology (ARVO). While researchers from many different ophthalmic fields are present at ARVO, it is the world’s largest gathering of retinal scientists. Continue Reading…

ARVO Update: Powerful Protein Positioned Well for Human Study

Dr. José Sahel

Dr. José Sahel

If you or someone you’re close to has a retinal degenerative disease, you should know about the vision-saving promise of a protein called Rod-derived Cone Viability Factor (RdCVF). It was discovered by Foundation-funded clinician-researchers Drs. José Sahel and Thierry Léveillard, of Institut de la Vision in Paris. In fact, they won the Foundation’s Board of Director’s Award in 2005 for the finding. It was a monumental effort, namely because they screened thousands of proteins to come up with the gem.

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ARVO Update: News on Gene Therapy Clinical Trials for RP and Choroideremia

Dr. Robert MacLaren

Dr. Robert MacLaren

I was very excited to learn here at ARVO that two early-stage gene therapy clinical trials – one for choroideremia taking place in the U.K., the other for autosomal recessive retinitis pigmentosa (arRP) caused by MERTK mutations underway in Saudi Arabia – are proceeding well thus far. It is important to keep in mind that safety is the primary focus in these Phase I studies.
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ARVO Poster: Nanoparticle Treatment Slows Vision Loss in Mice

ARVO Poster Hall - 2011The Sunday morning poster session at ARVO included a Foundation-funded research effort from Oklahoma University (OU) in which Dr. Lily Wong and her colleagues used a nanoceria treatment to slow retinal degeneration in a mouse model of autosomal dominant retinitis pigmentosa (adRP).

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Join Me (and 11,000 Other Eye Specialists) in Fort Lauderdale

I invite you to join me, this coming week, in sunny Fort Lauderdale, Florida – not for spring break, but for something even better. As is always the case this time of year, the Association for Research in Vision and Ophthalmology (ARVO) will host its international conference, providing thousands of eye professionals with the latest information on retinal research and technologies.

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Israel Update: Genetic Discovery Highlighted at Retinal Research Conference

Tel Aviv, Israel

Tel Aviv, Israel

Now that I’m back from my trip to Israel, I wanted to offer a couple more posts about my visit, the first covering a fascinating research conference in Tel Aviv.
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